Name :
PPIH Protein
Description :
Peptidyl-Prolyl Cis-Trans Isomerase H (PPIH) belongs to the Cyclophilin-type PPIase family that accelerate the folding of proteins. PPIases can catalyze the cis-trans isomerization of Proline Imidic peptide bonds in oligopeptides. PPIH participates in pre-mRNA splicing. It is a specific component of the complex that includes pre-mRNA processing factors PRPF3, PRPF4, and PRPF18, as well as U4/U5/U6 tri-snRNP. In addition, PPIH has PPIase activity and may play a role as a chaperone mediating the interactions between different proteins inside the spliceosome.
Species :
Human
Uniprotkb :
E. coli
Tag :
N-6His
Synonyms :
Peptidyl-Prolyl Cis-Trans Isomerase H, Rotamase H, PPIase H, Small Nuclear Ribonucleoprotein Particle-Specific Cyclophilin H, CypH, PPIH, U-snRNP-Associated Cyclophilin SnuCyp-20, CYP20, USA-CYP
Construction :
Recombinant Human Peptidyl-Prolyl Cis-Trans Isomerase H is produced by our E.coli expression system and the target gene encoding Met1-Met177 is expressed with a 6His tag at the N-terminus.
Protein Purity :
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight :
24 KDa, reducing conditions
Endotoxin :
Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulatione :
Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.
Reconstitution :
Stability & Storage :
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
Shipping :
The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below.
Research Background :
Peptidyl-Prolyl Cis-Trans Isomerase H (PPIH) belongs to the Cyclophilin-type PPIase family that accelerate the folding of proteins. PPIases can catalyze the cis-trans isomerization of Proline Imidic peptide bonds in oligopeptides. PPIH participates in pre-mRNA splicing. It is a specific component of the complex that includes pre-mRNA processing factors PRPF3, PRPF4, and PRPF18, as well as U4/U5/U6 tri-snRNP. In addition, PPIH has PPIase activity and may play a role as a chaperone mediating the interactions between different proteins inside the spliceosome.
References and Literature :
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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