Name :
SBDS Protein
Description :
The mutation of Shwachman-Bodian-Diamond syndrome (SBDS) gene has been proposed to be a major causative reason for SDS. Shwachman-Diamond syndrome (SDS) is a rare pediatric disease characterized by various systemic disorders, including hematopoietic dysfunction. SBDS deficiency leads to telomere shortening, that SBDS is a telomere-protecting protein that participates in regulating telomerase recruitment.
Species :
Human
Uniprotkb :
E. coli
Tag :
His
Synonyms :
CGI-97, Shwachman-Bodian-Diamond syndrome, SDS, SWDS
Construction :
A DNA sequence encoding the human SBDS (Q9Y3A5) (Met1-Glu250) was expressed with a polyhistidine tag at the N-terminus.
Protein Purity :
> 95 % as determined by SDS-PAGE
Molecular Weight :
Approxiamtely 31 kDa
Endotoxin :
Please contact us for more information.
Formulatione :
Lyophilized from sterile PBS, 10% glycerol. Please contact us for any concerns or special requirements. Normally 5 % – 8 % trehalose, mannitol and 0. 01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Reconstitution :
A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
Stability & Storage :
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Shipping :
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Research Background :
The mutation of Shwachman-Bodian-Diamond syndrome (SBDS) gene has been proposed to be a major causative reason for SDS. Shwachman-Diamond syndrome (SDS) is a rare pediatric disease characterized by various systemic disorders, including hematopoietic dysfunction. SBDS deficiency leads to telomere shortening, that SBDS is a telomere-protecting protein that participates in regulating telomerase recruitment.
References and Literature :
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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