Product Name :
CRT-0105950

Synonym :

Chemical Name :

CAS NO.:
1661845-86-8

Molecular formula :
C21H16ClN3OS

Molecular Weight:
393.9 g/mol

Classification :
MedChemExpress Products > Life Sciences > CRT-0105950

Description:
CRT-0105950 is a novel small-molecule drug that sensitizes ovarian cancer cells to cisplatin. CRT-0105950 binds to the miR-200 family of microRNAs and inhibits their function. CRT-0105950 has been shown to increase the sensitivity of ovarian tumor cells in vitro and in vivo to cisplatin, with no evidence of toxicity. The mechanism by which CRT-0105950 enhances cisplatin cytotoxicity is not yet known but may involve modulation of the cell cycle or suppression of tumor growth factors. This drug also has potential applications in monitoring ovarian cancer patients during chemotherapy and for determining the phenotype of cancer cells.

Purity :
>98%

Specifications :
10 mM * 1 mL

Price.:
193

Price unit :
$

Inventory :
In stock

MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.
Related websites: https://www.medchemexpress.com
2001-95-8 manufacturer 2589531-76-8 medchemexpress PMID:30020654 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com