Filipin III__Polyene macrolide antibiotic and antifungal Rigosertib (sodium)
Product Name
Filipin III
Description
Polyene macrolide antibiotic and antifungal
Purity
>98% (HPLC); UV (Conforms)
CAS No.
480-49-9
Molecular Formula
C35H58O11
Molecular Weight
654.83
Storage Temperature
-20ºC
Shipping Temperature
Blue Ice or 4ºC
Product Type
Antibiotic
Solubility
May be dissolved in methanol (10 mg/ml)
Source
From Streptomyces filipinensis
Appearance
White or slightly yellow powder
SMILES
CCCCCC(C1C(CC(CC(CC(CC(CC(CC(C(=CC=CC=CC=CC=CC(C(OC1=O)C)O)C)O)O)O)O)O)O)O)O
InChI
InChI=1S/C35H58O11/c1-4-5-11-16-31(42)34-33(44)22-29(40)20-27(38)18-25(36)17-26(37)19-28(39)21-32(43)23(2)14-12-9-7-6-8-10-13-15-30(41)24(3)46-35(34)45/h6-10,12-15,24-34,36-44H,4-5,11,16-22H2,1-3H3/b
InChIKey
IMQSIXYSKPIGPD-ZPXVTHDFSA-N
Safety Phrases
WHMIS Classification:
D2B Toxic Material Causing Other Toxic Effects Moderate skin irritant
Moderate respiratory irritant
Moderate eye irritant
GHS Classification:
Skin irritation (Category 2)
Eye irritation (Category 2A)
Specific target organ toxicity – single exposure (Category 3)
Signal word: Warning
Hazard statement(s):
H315 Causes skin irritation.
H319 Causes serious eye irritation.
H335 May cause respiratory irritation.
Precautionary statement(s):
P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray.
P264 Wash skin thoroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/ eye protection/ face protection.
P302 + P352 IF ON SKIN: Wash with plenty of soap and water.
P304 + P340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312 Call a POISON CENTER/doctor if you feel unwell.
P321 Specific treatment (see supplemental first aid instructions on this label).
P332 + P313 If skin irritation occurs: Get medical advice/ attention.
P337 + P313 If eye irritation persists: Get medical advice/ attention.
P362 Take off contaminated clothing and wash before reuse.
P403 + P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/ container to an approved waste disposal plant.
Cite This Product
Filipin III (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-551)
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/19124485
Alternative Names
Filipin, FILIPIN III, (17E,19E,21E,23E,25E)-4,6,8,10,12,14,16,27-octahydroxy-3-(1-hydroxyhexyl)-17,28-dimethyl-1-oxacyclooctacosa-17,19,21,23,25-pentaen-2-one, Filimirasin, Desoxylagosin
Research Areas
Cell Signaling, Metabolism, Mitochondrial Metabolism
PubChem ID
6433553
Polyene macrolide antibiotic and antifungal
D2B Toxic Material Causing Other Toxic Effects Moderate skin irritant
Moderate respiratory irritant
Moderate eye irritant
GHS Classification:
Skin irritation (Category 2)
Eye irritation (Category 2A)
Specific target organ toxicity – single exposure (Category 3)
Signal word: Warning
Hazard statement(s):
H315 Causes skin irritation.
H319 Causes serious eye irritation.
H335 May cause respiratory irritation.
Precautionary statement(s):
P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray.
P264 Wash skin thoroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/ eye protection/ face protection.
P302 + P352 IF ON SKIN: Wash with plenty of soap and water.
P304 + P340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312 Call a POISON CENTER/doctor if you feel unwell.
P321 Specific treatment (see supplemental first aid instructions on this label).
P332 + P313 If skin irritation occurs: Get medical advice/ attention.
P337 + P313 If eye irritation persists: Get medical advice/ attention.
P362 Take off contaminated clothing and wash before reuse.
P403 + P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/ container to an approved waste disposal plant.