Nitrendipine__L-type Ca channel blocker Dorsomorphin (dihydrochloride)
Product Name
Nitrendipine
Description
L-type Ca channel blocker
Purity
>98%
CAS No.
39562-70-4
Molecular Formula
C18H20N2O6
Molecular Weight
360.37
Storage Temperature
-20ºC
Shipping Temperature
Shipped Ambient
Product Type
Inhibitor
Solubility
Soluble to 25 mM in ethanol and to 50 mM in DMSO
Source
Synthetic
Appearance
Yellow Crystalline Solid
SMILES
CCOC(=O)C1=C(NC(=C(C1C2=CC(=CC=C2)N+(=O)O-)C(=O)OC)C)C
InChI
InChI=1S/C18H20N2O6/c1-5-26-18(22)15-11(3)19-10(2)14(17(21)25-4)16(15)12-7-6-8-13(9-12)20(23)24/h6-9,16,19H,5H2,1-4H3
InChIKey
PVHUJELLJLJGLN-UHFFFAOYSA-N
Safety Phrases
Classification: Caution: Substance not fully tested yet.
Safety Phrases:
S22 – Do not breathe dust
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection
S24/25- Avoid contact with shin and eyes
Risk Phrases:
R62 – Possible risk of impaired fertility
Hazard Phrases:
H312-H332
Precautionary Phrases:
P280
Cite This Product
Nitrendipine (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-320)
Alternative Names
Ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylate
Research Areas
Calcium Channels, Ion Channels, Neuroscience, Voltage-Gated Calcium Channels
PubChem ID
11931106
Scientific Background
Nitrendipine is a dihydropyridine calcium channel blocker. It does so by binding effectively with the L-type calcium channels in smooth muscles thereby inactivating it and reducing the influx of calcium.
References
1. Peterson B.Z., Tanada T.N., Catterall W.A. (1996) J Biol Chem. 271: 5293-5296.
L-type Ca channel blocker
Safety Phrases:
S22 – Do not breathe dust
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection
S24/25- Avoid contact with shin and eyes
Risk Phrases:
R62 – Possible risk of impaired fertility
Hazard Phrases:
H312-H332
Precautionary Phrases:
P280