Phytosphingosine__Kinase Activator NBI-74331
Product Name
Phytosphingosine
Description
Kinase Activator
Purity
>98% (TLC); NMR (Conforms)
CAS No.
554-62-1
Molecular Formula
C18H39NO3
Molecular Weight
317.5
Storage Temperature
-20ºC
Shipping Temperature
Shipped Ambient
Product Type
Activator
Solubility
Soluble to 2 mg/ml in ethanol
Source
Isolated from Saccharomyces cerevisiae
Appearance
White powder
SMILES
CCCCCCCCCCCCCCemail protected(email protected(email protected(CO)N)O)O
InChI
InChI=1S/C18H39NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17(21)18(22)16(19)15-20/h16-18,20-22H,2-15,19H2,1H3/t16-,17+,18-/m0/s1
InChIKey
AERBNCYCJBRYDG-KSZLIROESA-N
Safety Phrases
Classification: Not WHMIS controlled.
Safety Phrases:
S22 – Do not breathe dust.
S24/25 – Avoid contact with skin and eyes.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.
Cite This Product
Phytosphingosine (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-524)
Alternative Names
(2S,3R,4R)-Octadecane-1,2,3,4-tetraol
Research Areas
Cancer, Oxidative Stress
PubChem ID
122121
Scientific Background
Phytosphingosine is a naturally occurring component found in yeast, plants and animals. In yeast, it is involved in mediating the heat stress response. Phytosphingosine has been found to be pro-apoptotic in certain cancer cell lines. It is thought to activate the p38 MAPK pathway, followed by release of cytochrome c and activation of caspase 3, ultimately leading to programed cell death.
References
1. Fischer C., et al. (2013) Skin Pharmacol Physiol. 26(1): 36-44.
Kinase Activator
Safety Phrases:
S22 – Do not breathe dust.
S24/25 – Avoid contact with skin and eyes.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.