Piceatannol

Piceatannol__SIRT1 activator SP2510

Product Name Piceatannol
Description

SIRT1 activator

Purity >98% (TLC); NMR (Conforms)
CAS No. 10083-24-6
Molecular Formula C14H12O4
Molecular Weight 244.2
Storage Temperature -20ºC
Shipping Temperature Shipped Ambient
Product Type Activator
Solubility Soluble in 10 mg/ml DMSO or 10 mg/ml Ethanol
Source Synthetic
Appearance Light Pink Solid
SMILES C1=CC(=C(C=C1/C=C/C2=CC(=CC(=C2)O)O)O)O
InChI InChI=1S/C14H12O4/c15-11-5-10(6-12(16)8-11)2-1-9-3-4-13(17)14(18)7-9/h1-8,15-18H/b2-1+
InChIKey CDRPUGZCRXZLFL-OWOJBTEDSA-N
Safety Phrases Classification: Caution- Substance not yet fully tested.
Safety Phrases:
S22 – Do not breathe dust
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection
S24/25- Avoid contact with skin and eyes
Cite This Product Piceatannol (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-358)
Alternative Names 3,3′,4,5′-Tetrahydroxy-transstilbene; 4-(E)-2-(3,5-Dihydroxyphenyl)vinyl-1,2-benzenediol
Research Areas Cell Signaling, Epigenetics
PubChem ID 667639
Scientific Background A naturally occurring resveratrol analog. Inhibits nonreceptor kinases Syk and Lyk (IC50=ca. 10M) (1). Stimulates Sirt1 (2).
References 1. Seow C.J., et al. (2002) Eur. J. Pharmacol. 443: 189.
2. Howitz K.T., et al. (2003) Nature 425: 191.