Ponasterone A__Ecdysteroid Enzastaurin
Product Name
Ponasterone A
Description
Ecdysteroid
Purity
>99%
CAS No.
13408-56-5
Molecular Formula
C27H44O6
Molecular Weight
464.6
Storage Temperature
-20ºC
Shipping Temperature
Shipped Ambient
Product Type
Inducer
Solubility
Soluble in acetic acid; 100% ethanol; methanol; DMSO. Insoluble in water.
Source
Isolated
Appearance
Off white solid
SMILES
C@@34(C2=CC(C@@H1CC@@H(O)email protected(CC@@1(email protected2CCC@@3(C@@H(C@(C@@H(CCC(C)C)O)(O)C)CC4)C)C)O)=O)O
InChI
InChI=1S/C27H44O6/c1-15(2)6-7-23(31)26(5,32)22-9-11-27(33)17-12-19(28)18-13-20(29)21(30)14-24(18,3)16(17)8-10-25(22,27)4/h12,15-16,18,20-23,29-33H,6-11,13-14H2,1-5H3/t16-,18-,20+,21-,22-,23+,24+,25+,
InChIKey
PJYYBCXMCWDUAZ-JJJZTNILSA-N
Safety Phrases
Classification: Not WHMIS controlled.
Safety Phrases:
S22 – Do not breathe dust.
S24/25 – Avoid contact with skin and eyes.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.
Cite This Product
Ponasterone A (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-419)
Alternative Names
25-Deoxy-20-hydroxyecdysone, 25-Deoxyecdysterone, 2β,3β,14α,20R,22R-Pentahydroxy-5β-cholest-7-en-6-one
Research Areas
Cell Signaling, Neuroscience
PubChem ID
115127
Scientific Background
Ponasterone A is a naturally occurring insect hormone, involved in regulating metamorphosis. Ponasterone A is a functionally substitute to muristerone A, which is an inducer of the ecdysone mammalian expression system and is also able to induce β-galactosidase expression.
References
1. Xiao Y., Beilstein M., Wang M., Purintrapiban J., & Forsberg N. (2003) Int J Biochem Cell Biol. 79-85.
2. Albanese C., Reutens A., Bouzahzah B., Fu M., D'Amico M., Link T., et al. (2000) FASEB J. 877-84.
Ecdysteroid
Safety Phrases:
S22 – Do not breathe dust.
S24/25 – Avoid contact with skin and eyes.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.
2. Albanese C., Reutens A., Bouzahzah B., Fu M., D'Amico M., Link T., et al. (2000) FASEB J. 877-84.