Resveratrol__Antioxidant Celastrol
Product Name
Resveratrol
Description
Antioxidant
Purity
>98%
CAS No.
501-36-0
Molecular Formula
C14H12O3
Molecular Weight
228.25
Storage Temperature
-20ºC
Shipping Temperature
Shipped Ambient
Product Type
Antioxidant
Solubility
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Source
Synthetic
Appearance
Off-White Solid
SMILES
C1=CC(=CC=C1/C=C/C2=CC(=CC(=C2)O)O)O
InChI
InChI=1S/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H/b2-1+
InChIKey
LUKBXSAWLPMMSZ-OWOJBTEDSA-N
Safety Phrases
Classification: Caution: Substance not yet fully tested.
Safety Phrases:
S22 – Do not breathe dust
S24/25 – Avoid contact with skin and eyes
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection
Hazard Phrases:
H302-H315-H317-H318-H335
Precautionary Phrases:
P261-P280-P305 + P351 + P338
Cite This Product
Resveratrol (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-264)
Alternative Names
5-(E)-2-(4-Hydroxyphenyl)vinyl-1,3-benzenediol
Research Areas
Cancer, Oxidative Stress
PubChem ID
445154
Scientific Background
Resveratrol is a stilbenoid and a phytoalexin produced naturally by several plants. Its effects are numerous and include anti-cancer (1), anti-inflammatory (2), anti-fungal and has other beneficial cardiovascular effects.
It has been proposed that Mn SOD is increased by the pathwayRESV-SIRT1/Nad+- FOXO3a- MnSOD (3). In terms of its anti-cancer properties, resveratrol modulates the transcription factor NF-KB and inhibition of the cytochrome P450 enzyme (1, 4).
References
1. Leiro J., et al. (2005) Int Immunopharm. 5(2): 393-406.
2. Gentilli M., et al. (2001) Life Sciences. 68(11): 1317-1321.
3. Robb E.L., et al. (2008) Biochem Biophys Res Commun. 367(2): 406-412.
4. Chun Y.J., Kim M.Y., Guengerich F.P. (1999) Biochem Biophys Res Commun. 262(1): 20-24.
Antioxidant
Safety Phrases:
S22 – Do not breathe dust
S24/25 – Avoid contact with skin and eyes
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection
Hazard Phrases:
H302-H315-H317-H318-H335
Precautionary Phrases:
P261-P280-P305 + P351 + P338
It has been proposed that Mn SOD is increased by the pathwayRESV-SIRT1/Nad+- FOXO3a- MnSOD (3). In terms of its anti-cancer properties, resveratrol modulates the transcription factor NF-KB and inhibition of the cytochrome P450 enzyme (1, 4).
2. Gentilli M., et al. (2001) Life Sciences. 68(11): 1317-1321.
3. Robb E.L., et al. (2008) Biochem Biophys Res Commun. 367(2): 406-412.
4. Chun Y.J., Kim M.Y., Guengerich F.P. (1999) Biochem Biophys Res Commun. 262(1): 20-24.