Retinoic acid

Posted by

Retinoic acid__Retinoid RAR agonist VX-810

Product Name Retinoic acid
Description

Retinoid RAR agonist
Purity >98%
CAS No. 302-79-4
Molecular Formula C20H28O2
Molecular Weight 300.44
Storage Temperature -20ºC
Shipping Temperature Shipped Ambient
Product Type Agonist
Solubility Soluble to 50 mM in ethanol and 25 mM in DMSO
Source Synthetic
Appearance Yellow solid
SMILES CC1=C(C(CCC1)(C)C)/C=C/C(=C/C=C/C(=C/C(=O)O)/C)/C
InChI InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+
InChIKey SHGAZHPCJJPHSC-YCNIQYBTSA-N
Safety Phrases Classification: Toxic. May be harmful or fatal is inhaled, swallowed or absorbed through skin.
Safety Phrases:
S22 – Do not breathe dust
S24/25 – Avoid contact with skin and eyes
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection
Risk Phrases:
R20/21/22 – Harmful by inhilation, in contact with skin and if swallowed
R40 – Limited evidence of a carcinogenic effect
R46 – May cause heritable genetic damage
R62 – Possible risk of impaired fertility
Hazard Phrases:
H302-H411
Precautionary Phrases:
P273
Cite This Product Retinoic acid (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-258)
Alternative Names Tretinoin, ATRA
Research Areas Cancer, Apoptosis
PubChem ID 444795
Scientific Background Retinoic acid is a metabolite of Vitamin A that mediates the functions of vitamin A required for growth and development. It is generated in a specific region of the embryo during early embryonic development (1).
References 1. Duester G. (2008) Cell. 134: 921-931.