SL-01__p53/mdm2 inhibitor Tafamidis
Product Name
SL-01
Description
p53/mdm2 inhibitor
Purity
>98% (TLC); NMR (Conforms)
CAS No.
26049-94-5
Molecular Formula
C18H18ClNO3
Molecular Weight
331.8
Storage Temperature
-20ºC
Shipping Temperature
Shipped Ambient
Product Type
Inhibitor
Solubility
Soluble in 50 mg/ml DMSO oir 15 mg/ml warm Ethanol
Source
Synthetic
Appearance
White Solid
SMILES
C1=CC=C(C=C1)CC@@H(C(=O)CCl)NC(=O)OCC2=CC=CC=C2
InChI
InChI=1S/C18H18ClNO3/c19-12-17(21)16(11-14-7-3-1-4-8-14)20-18(22)23-13-15-9-5-2-6-10-15/h1-10,16H,11-13H2,(H,20,22)/t16-/m0/s1
InChIKey
OYHLRJGDELITAF-INIZCTEOSA-N
Safety Phrases
Classification: Caution – Substance not yet fully tested.
Safety Phrases:
S22 – Do not breathe dust
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection
S24/25- Avoid contact with skin and eyes
Cite This Product
SL-01 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-343)
Alternative Names
Benzyl (2S)-4-chloro-3-oxo-1-phenyl-2-butanylcarbamate; N-Benzyloxycarbonyl-Lphenylalaninylchloromethyl ketone; ZPCK
Research Areas
Cancer, Apoptosis, Cancer Growth Inhibitors, p53/mdm2 Inhibitors
PubChem ID
99625
Scientific Background
Inhibits the p53-MDM2 interaction (20 µM). Has also been shown to inhibit bovine chymotrypsin A-y.
References
1. Li J., et al. (2011) J Biol Screening 16: 450.
p53/mdm2 inhibitor
Safety Phrases:
S22 – Do not breathe dust
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection
S24/25- Avoid contact with skin and eyes