TG003__Clk family kinase inhibitor TMC353122
Product Name
TG003
Description
Clk family kinase inhibitor
Purity
>98%
CAS No.
719277-26-6
Molecular Formula
C13H15NO2S
Molecular Weight
249.3
Storage Temperature
-20ºC
Shipping Temperature
Shipped Ambient
Product Type
Inhibitor
Solubility
Soluble to 100 mM in DMSO and to 75 mM in ethanol
Source
Synthetic
Appearance
Yellow solid
SMILES
CCN1C2=C(C=CC(=C2)OC)S/C1=CC(=O)C
InChI
InChI=1S/C13H15NO2S/c1-4-14-11-8-10(16-3)5-6-12(11)17-13(14)7-9(2)15/h5-8H,4H2,1-3H3/b13-7-
InChIKey
BGVLELSCIHASRV-QPEQYQDCSA-N
Safety Phrases
Classification:
Not a hazardous substance or mixture.
Safety Phrases:
S22 – Do not breathe dust.
S24/25 – Avoid contact with skin and eyes.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.
Cite This Product
TG003 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-515)
Alternative Names
TG 003, (1Z)-1-(3-Ethyl-5-methoxy-2(3H)-benzothiazolylidene)-2-propanone
Research Areas
Cancer, Apoptosis, Cancer Growth Inhibitors, Cell Signaling, Tyrosine Kinase Inhibitors
PubChem ID
1893668
Scientific Background
TG003 is a potent inhibitor of the CDC-like (Clk) family kinases. It has been shown to suppress serine/arginine-rich protein phosphorylation.
References
1. Muraki M., et al. (2004) J. Biol. Chem. 279(23): 24246–24254.
Clk family kinase inhibitor
Not a hazardous substance or mixture.
Safety Phrases:
S22 – Do not breathe dust.
S24/25 – Avoid contact with skin and eyes.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.