Tolcapone__COMT inhibitor IDO-IN-5
Product Name
Tolcapone
Description
COMT inhibitor
Purity
>98% (TLC); NMR (Conforms)
CAS No.
134308-13-7
Molecular Formula
C14H11NO5
Molecular Weight
273.2
Storage Temperature
-20ºC
Shipping Temperature
Shipped Ambient
Product Type
Inhibitor
Solubility
Soluble in DMSO (25 mg/ml), or ethanol (25 mg/ml)
Source
Synthetic
Appearance
Yellow powder
SMILES
Cc1ccc(cc1)C(=O)c2cc(O)c(O)c(c2)N+(O-)=O
InChI
1S/C14H11NO5/c1-8-2-4-9(5-3-8)13(17)10-6-11(15(19)20)14(18)12(16)7-10/h2-7,16,18H,1H3
InChIKey
MIQPIUSUKVNLNT-UHFFFAOYSA-N
Safety Phrases
Classification:
Not WHMIS controlled
Hazard statement(s):
H303 – May be harmful if swallowed.
H400 – Very toxic to aquatic life.
Precautionary statement(s)
P273 Avoid release to the environment.
Cite This Product
Tolcapone (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-540)
Alternative Names
(3,4-dihydroxy-5-nitrophenyl)-(4-methylphenyl)methanone, Tolcapone, Tasmar, Ro 40-7592
Research Areas
Neurodegeneration, Neuroscience, Parkinson_s Disease
PubChem ID
4659569
Scientific Background
Tolcapone is a COMT inhibitor. It inhibits both central and peripheral nervous system catechol-O-methyltransferase (COMT).
COMT inhibitor
Not WHMIS controlled
Hazard statement(s):
H303 – May be harmful if swallowed.
H400 – Very toxic to aquatic life.
Precautionary statement(s)
P273 Avoid release to the environment.