Triacsin C__Acyl-CoA synthetase inhibitor RGFP967
Product Name
Triacsin C
Description
Acyl-CoA synthetase inhibitor
Purity
>98%
CAS No.
76896-80-5
Molecular Formula
C11H17N3O
Molecular Weight
207.27
Storage Temperature
-20ºC
Shipping Temperature
Shipped Ambient
Product Type
Inhibitor
Solubility
Soluble in DMSO (25 mg/ml) or methanol (5 mg/ml)
Source
Synthetic
Appearance
Oil dissolved in DMSO (1mg/ml)
SMILES
CCC/C=C/C/C=C/C=C/C=N/NN=O
InChI
InChI=1S/C11H17N3O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15/h4-5,7-11H,2-3,6H2,1H3,(H,13,15)/b5-4+,8-7+,10-9+,12-11+
InChIKey
NKTGCVUIESDXPU-YLEPRARLSA-N
Safety Phrases
Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin.
Safety Phrases:
S22 – Do not breathe dust
S24/25 – Avoid contact with skin and eyes
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection
Cite This Product
Triacsin C (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-203)
Alternative Names
(3E)-1-Oxo-3-(2E,4E,7E)-2,4,7-undecatrien-1-ylidenetriazane
Research Areas
Cancer, Apoptosis
PubChem ID
9576787
Scientific Background
Triacsin C is a potent inhibitor of long fatty acyl CoA synthetase. It blocks beta-cell apoptosis. It also blocks the de novo synthesis of triglyercides, diglycerides and cholesterol esters, interfering with lipid metabolism (1). It is also a potent vasodilator.
References
1. Igal R.A., Wang P., Coleman R.A. (1997) Biochem J. 324(Pt2): 529-534.
Acyl-CoA synthetase inhibitor
Safety Phrases:
S22 – Do not breathe dust
S24/25 – Avoid contact with skin and eyes
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection