Verapamil HCl__L-type Ca channel blocker Rucaparib (phosphate)
Product Name
Verapamil HCl
Description
L-type Ca channel blocker
Purity
>98%
CAS No.
152-11-4
Molecular Formula
C27H38N2O4•HCl
Molecular Weight
491.07
Storage Temperature
-20ºC
Shipping Temperature
Shipped Ambient
Product Type
Inhibitor
Solubility
Soluble to 100 mM in ethanol and to 50 mM in water
Source
Synthetic
Appearance
White Solid
SMILES
CC(C)C(CCCN(C)CCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C=C2)OC)OC.Cl
InChI
InChI=1S/C27H38N2O4.ClH/c1-20(2)27(19-28,22-10-12-24(31-5)26(18-22)33-7)14-8-15-29(3)16-13-21-9-11-23(30-4)25(17-21)32-6;/h9-12,17-18,
InChIKey
DOQPXTMNIUCOSY-UHFFFAOYSA-N
Safety Phrases
Classification: Toxic. May be harmful or fatal if inhaled, swallowed or absorbed through skin.
Safety Phrases:
S22 – Do not breathe dust
S24/25 – Avoid contact with skin and eyes
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection
S45 – In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible)
Risk Phrases:
R23/24/25 – Toxic by inhilation, in contact with skin and if swallowed
R60 – May impair fertility
R61 – May cause harm to the unborn child
R68 – Possible risk of irreversible effects
Hazard Phrases:
H301-H311-H331
Precautionary Phrases:
P261-P280-P301 + P310-P311
Cite This Product
Verapamil HCl (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-308)
Alternative Names
2-(3,4-Dimethoxyphenyl)-5-{2-(3,4-dimethoxyphenyl)ethyl(methyl)amino}-2-isopropylpentanenitrile hydrochloride (1:1)
Research Areas
Calcium Channels, Ion Channels, Neuroscience, Voltage-Gated Calcium Channels
PubChem ID
62969
Scientific Background
Verapamil is an L-type calcium channel blocker of the phenylalkylamine class. It has been used in the treatment of hypertension, angina pectoris, cardiac arrhythmia, and cluster headaches. Its mechanism is to block voltage-dependent calcium channels (1).
References
1. Livesley B., and Oram S. (1972) Br Med J. 2(5804): 50.
L-type Ca channel blocker
Safety Phrases:
S22 – Do not breathe dust
S24/25 – Avoid contact with skin and eyes
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection
S45 – In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible)
Risk Phrases:
R23/24/25 – Toxic by inhilation, in contact with skin and if swallowed
R60 – May impair fertility
R61 – May cause harm to the unborn child
R68 – Possible risk of irreversible effects
Hazard Phrases:
H301-H311-H331
Precautionary Phrases:
P261-P280-P301 + P310-P311