Veratridine__Na channel activator SCH 546740
Product Name
Veratridine
Description
Na channel activator
Purity
>98%
CAS No.
71-62-5
Molecular Formula
C36H51NO11
Molecular Weight
673.79
Storage Temperature
-20ºC
Shipping Temperature
Shipped Ambient
Product Type
Activator
Solubility
Soluble in DMSO (25 mg/ml) or 100% ethanol (25 mg/ml)
Source
Synthetic
Appearance
White solid
SMILES
Cemail protected1CCemail protected2C@@(C@3(email protected(CC@4(C@@H5CCemail protected6C@7(C@5(CC@4(C@@H3CN2C1)O)OC@@6(email protected(CC7)OC(=O)C8=CC(=C(C=C8)OC)OC)O)C)O)O)O)(C)O
InChI
InChI=1S/C36H51NO11/c1-19-6-11-26-31(3,40)35(43)25(17-37(26)16-19)33(42)18-34-24(32(33,41)15-27(35)38)10-9-23-30(34,2)13-12-28(36(23,44)48-34)47-29
InChIKey
FVECELJHCSPHKY-UIHGVQCZSA-N
Safety Phrases
Classification: Caution: Substance not yet fully tested.
Safety Phrases:
S22 – Do not breathe dust
S24/25 – Avoid contact with skin and eyes
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection
Hazard Phrases:
H302-H315-H317-H318-H335
Precautionary Phrases: P261-P280-P305 + P351 + P338
Cite This Product
Veratridine (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-300)
Alternative Names
(3β,4α,16β)-4,12,14,16,17,20-Hexahydroxy-4,9-epoxycevan-3-yl 3,4-dimethoxybenzoate
Research Areas
Ion Channels, Neuroscience, Sodium Channels
PubChem ID
6280
Scientific Background
Veratridine is a steroid-derived alkaloid that functions as a neurotoxin by activating sodium channels. It binds to intramembrane receptor site 2 thereby increasing intracellular Ca2+ concentration.
References
1. Sperelakis N., Pappano A.J. (1969) J Gen Physiol. 53(1): 97-114.
Na channel activator
Safety Phrases:
S22 – Do not breathe dust
S24/25 – Avoid contact with skin and eyes
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection
Hazard Phrases:
H302-H315-H317-H318-H335
Precautionary Phrases: P261-P280-P305 + P351 + P338