XAV939__Tankyrase inhibitor NLG921
Product Name
XAV939
Description
Tankyrase inhibitor
Purity
>98% (HPLC); NMR (conforms)
CAS No.
284028-89-3
Molecular Formula
C14H11F3N2OS
Molecular Weight
312.3
Storage Temperature
-20ºC
Shipping Temperature
Shipped Ambient
Product Type
Inhibitor
Solubility
Soluble in DMSO (25 mg/ml)
Source
Synthetic
Appearance
Off white powder
SMILES
c1cc(ccc1c2nHc(=O)c3c(n2)CCSC3)C(F)(F)F
InChI
InChI=1S/C14H11F3N2OS/c15-14(16,17)9-3-1-8(2-4-9)12-18-11-5-6-21-7-10(11)13(20)19-12/h1-4H,5-7H2,(H,18,19,20)
InChIKey
KLGQSVMIPOVQAX-UHFFFAOYSA-N
Safety Phrases
Classification:
D1B Toxic Material Causing Immediate and Serious Toxic Effects – Toxic by ingestion
D2B Toxic Material Causing Other Toxic Effects Moderate eye irritant
Hazard statement(s):
H301 Toxic if swallowed.
H319 Causes serious eye irritation.
Precautionary statement(s):
P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/ physician.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Cite This Product
XAV939 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-532)
Alternative Names
3,5,7,8-Tetrahydro-2-4-(trifluoromethyl)phenyl-4H-thiopyrano4,3-dpyrimidin-4-one
Research Areas
Cell Signaling, Epigenetics and Nuclear Signalling
PubChem ID
2726824
Scientific Background
XAV939 is a potent tankyrase (TNKS) inhibitor, as well as a Wnt inhibitor and beta-catenin inhibitor.
Tankyrase inhibitor
D1B Toxic Material Causing Immediate and Serious Toxic Effects – Toxic by ingestion
D2B Toxic Material Causing Other Toxic Effects Moderate eye irritant
Hazard statement(s):
H301 Toxic if swallowed.
H319 Causes serious eye irritation.
Precautionary statement(s):
P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/ physician.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.