ZM 306416__VEGFR kinase inhibitor Mc-Val-Cit-PABC-PNP
Product Name
ZM 306416
Description
VEGFR kinase inhibitor
Purity
>98% (TLC)
CAS No.
690206-97-4
Molecular Formula
C16H13ClFN3O2
Molecular Weight
333.7
Storage Temperature
-20ºC
Shipping Temperature
Shipped Ambient
Product Type
Inhibitor
Solubility
Soluble in DMSO (3 mg/ml) or ethanol (1 mg/ml)
Source
Synthetic
Appearance
Off-white solid
SMILES
COC1=C(C=C2C(=C1)C(=NC=N2)NC3=C(C=C(C=C3)Cl)F)OC
InChI
InChI=1S/C16H13ClFN3O2/c1-22-14-6-10-13(7-15(14)23-2)19-8-20-16(10)21-12-4-3-9(17)5-11(12)18/h3-8H,1-2H3,(H,19,20,21)
InChIKey
YHUIUSRCUKUUQA-UHFFFAOYSA-N
Safety Phrases
Classification:
Not a hazardous substance or mixture.
Safety Phrases:
S22 – Do not breathe dust.
S24/25 – Avoid contact with skin and eyes.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.
Cite This Product
ZM 306416 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-487)
Alternative Names
ZM-306416
Research Areas
Cancer, Apoptosis, Cancer Growth Inhibitors, Cardiovascular System, Cell Signaling, Tyrosine Kinase Inhibitors
PubChem ID
5329006
Scientific Background
ZM 306416 is a potent and selective VEGF receptor tyrosine kinase inhibitor. Specifically, it inhibits Flk-1 (KDR) and Flt.
References
1. Hennequin L.F., et al. (1999) J. Med. Chem. 42(26): 5369–5389.
2. Kawai, T., et al. (2006) Neurosci. 141(3): 1209–1216.
VEGFR kinase inhibitor
Not a hazardous substance or mixture.
Safety Phrases:
S22 – Do not breathe dust.
S24/25 – Avoid contact with skin and eyes.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.
2. Kawai, T., et al. (2006) Neurosci. 141(3): 1209–1216.