Zafirlukast__Hsp70 inhibitor PND-1188
Product Name
Zafirlukast
Description
Hsp70 inhibitor
Purity
>98% (TLC); NMR (Conforms)
CAS No.
107753-78-6
Molecular Formula
C31H33N3O6S
Molecular Weight
575.7
Storage Temperature
-20ºC
Shipping Temperature
Shipped Ambient
Product Type
Inhibitor
Solubility
Soluble in 25 mg/ml DMSO
Source
Synthetic
Appearance
White to Pink Solid
SMILES
CC1=CC=CC=C1S(=O)(=O)NC(=O)C2=CC(=C(C=C2)CC3=CN(C4=C3C=C(C=C4)NC(=O)OC5CCCC5)C)OC
InChI
InChI=1S/C31H33N3O6S/c1-20-8-4-7-11-29(20)41(37,38)33-30(35)22-13-12-21(28(17-22)39-3)16-23-19-34(2)27-15-14-24(18-26(23)27)32-31(36)40-25-9-5-6-10-25/h4,7-8,11-15,17-19,25H,5-6,9-10,16H2,1-3H3,(H,32
InChIKey
YEEZWCHGZNKEEK-UHFFFAOYSA-N
Safety Phrases
Classification: Caution- Substance not yet fully tested.
Safety Phrases:
S22 – Do not breathe dust
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection
S24/25- Avoid contact with skin and eyes
Cite This Product
Zafirlukast (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-361)
Alternative Names
Cyclopentyl 3-(2-methoxy-4-{(2-methylphenyl)sulfonylcarbamoyl}benzyl)-1-methyl-1H-indol-5-ylcarbamate; ICI-204219
Research Areas
Cancer, Heat Shock
PubChem ID
5717148
Scientific Background
HSP70 inhibitor ( IC50=37 µM). Leukotriene antagonist. Clinically useful antiasthmatic agent. Cell permeable. Looking for more information on HSP70? Visit our new HSP70 Scientific Resource Guide at http://www.HSP70.com.
References
1. Miyata Y., et al. (2010) J. Biomol. 15: 1211.
Hsp70 inhibitor
Safety Phrases:
S22 – Do not breathe dust
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection
S24/25- Avoid contact with skin and eyes