Quisqualic Acid__Glutamate receptor agonist Ponatinib
Product Name
Quisqualic Acid
Description
Glutamate receptor agonist
Purity
99.2%
CAS No.
52809-07-1
Molecular Formula
C5H7N3O5
Molecular Weight
189.13
Storage Temperature
-20ºC
Shipping Temperature
Shipped Ambient
Product Type
Agonist
Solubility
Soluble to 100 mM in 1eq. NaOH; 10 mM in water
Source
Isolated from Quisqualis fructus
Appearance
Off white solid
SMILES
email protected(N)(CN1OC(=O)NC1=O)C(=O)O
InChI
InChI=1S/C5H7N3O5/c6-2(3(9)10)1-8-4(11)7-5(12)13-8/h2H,1,6H2,(H,9,10)(H,7,11,12)/t2-/m0/s1
InChIKey
ASNFTDCKZKHJSW-REOHCLBHSA-N
Safety Phrases
Classification: Not WHMIS controlled.
Safety Phrases:
S22 – Do not breathe dust.
S24/25 – Avoid contact with skin and eyes.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.
Hazard statements:
H302 + H312 Harmful if swallowed or in contact with skin
H332 Harmful if inhaled.
Precautionary statements:
P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray.
P264 Wash skin thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/ protective clothing.
P301 + P312 IF SWALLOWED: Call a POISON CENTER or doctor/ physician if you feel unwell.
P302 + P352 IF ON SKIN: Wash with plenty of soap and water.
P304 + P340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P312 Call a POISON CENTER or doctor/ physician if you feel unwell.
P322 Specific measures (see supplemental first aid instructions on this label).
P330 Rinse mouth.
P363 Wash contaminated clothing before reuse.
P501 Dispose of contents/ container to an approved waste disposal plant.
Cite This Product
Quisqualic Acid (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-418)
Alternative Names
(L)-(+)-α-Amino-3,5-dioxo-1,2,4-oxadiazolidine-2-propanoic acid
Research Areas
AMPA Receptors, Glutamate Receptors, Ion Channels, Neuroscience, Neurotransmitter Receptors
PubChem ID
40539
Scientific Background
Quisqualic acid is a glutamate receptor and AMPA ionotropic receptors agonist. It is also known to sensitize neurons in hippocampus to depolarization by L-AP6.
References
1. Schulte M., Roon R., Chalmers D., Sunter D., & Koerner J. (1994) Brain Res. 203-7.
2. Schoepp D., & Conn P. (1993) Trends Pharmacol Sci. 13-20.
Glutamate receptor agonist
Safety Phrases:
S22 – Do not breathe dust.
S24/25 – Avoid contact with skin and eyes.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.
Hazard statements:
H302 + H312 Harmful if swallowed or in contact with skin
H332 Harmful if inhaled.
Precautionary statements:
P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray.
P264 Wash skin thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/ protective clothing.
P301 + P312 IF SWALLOWED: Call a POISON CENTER or doctor/ physician if you feel unwell.
P302 + P352 IF ON SKIN: Wash with plenty of soap and water.
P304 + P340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P312 Call a POISON CENTER or doctor/ physician if you feel unwell.
P322 Specific measures (see supplemental first aid instructions on this label).
P330 Rinse mouth.
P363 Wash contaminated clothing before reuse.
P501 Dispose of contents/ container to an approved waste disposal plant.
2. Schoepp D., & Conn P. (1993) Trends Pharmacol Sci. 13-20.