SB-366791__TRPV1 blocker Bitopertin
Product Name
SB-366791
Description
TRPV1 blocker
Purity
>98%
CAS No.
472981-92-3
Molecular Formula
C16H14CINO2
Molecular Weight
287.75
Storage Temperature
-20ºC
Shipping Temperature
Shipped Ambient
Product Type
Inhibitor
Solubility
Soluble to 10 mM in ethanol and to 100 mM in DMSO
Source
Synthetic
Appearance
White solid
SMILES
COC1=CC=CC(=C1)NC(=O)/C=C/C2=CC=C(C=C2)Cl
InChI
InChI=1S/C16H14ClNO2/c1-20-15-4-2-3-14(11-15)18-16(19)10-7-12-5-8-13(17)9-6-12/h2-11H,1H3,(H,18,19)/b10-7+
InChIKey
RYAMDQKWNKKFHD-JXMROGBWSA-N
Safety Phrases
Classification: Caution: Substance not fully tested yet.
Safety Phrases:
S22 – Do not breathe dust
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection
S24/25- Avoid contact with shin and eyes
Cite This Product
SB-366791 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-321)
Alternative Names
(2E)-3-(4-Chlorophenyl)-N-(3-methoxyphenyl)acrylamide, N-(3-Methoxyphenyl)-4-chlorocinnamide
Research Areas
Ion Channels, Neuroscience, Transient Receptor Potential Channels
PubChem ID
667594
Scientific Background
A potent and selective vanilloid receptor (TRPV1) antagonist. An effective antagonist of hTRPV1 when stimulated by capsaicin, acid, or noxious heat.
References
1. Gunthorpe M.J., et al. (2004) Neuropharmacology. 46(1): 133-149.
TRPV1 blocker
Safety Phrases:
S22 – Do not breathe dust
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection
S24/25- Avoid contact with shin and eyes