Sorafenib__Raf-1 kinase inhibitor BAY 87-2244
Product Name
Sorafenib
Description
Raf-1 kinase inhibitor
Purity
>99%
CAS No.
284461-73-0
Molecular Formula
C21H16ClF3N4O3
Molecular Weight
464.8
Storage Temperature
-20ºC
Shipping Temperature
Shipped Ambient
Product Type
Inhibitor
Solubility
Soluble inDMSO (200mg/ml) or ethanol (3mg/ml)
Source
Synthetic
Appearance
Off white powder
SMILES
CNC(=O)c1cc(ccn1)Oc2ccc(cc2)NC(=O)Nc3ccc(c(c3)C(F)(F)F)Cl
InChI
InChI=1S/C21H16ClF3N4O3/c1-26-19(30)18-11-15(8-9-27-18)32-14-5-2-12(3-6-14)28-20(31)29-13-4-7-17(22)16(10-13)21(23,24)25/h2-11H,1H3,(H,26,30)(H2,28,29,31)
InChIKey
MLDQJTXFUGDVEO-UHFFFAOYSA-N
Safety Phrases
Classification:
Not a hazardous substance or mixture.
Safety Phrases:
S22 – Do not breathe dust.
S24/25 – Avoid contact with skin and eyes.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.
Cite This Product
Sorafenib (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-476)
Alternative Names
4-4-4-chloro-3-(trifluoromethyl)phenylcarbamoylaminophenoxy-N-methylpyridine-2-carboxamide; 4-methylbenzenesulfonic acid
Research Areas
Cell Signaling
PubChem ID
216239
Scientific Background
Sorafenib display inhibition of multiple kinase targets including, VEGFR, PDGFR, and Raf.
References
1. Juan, L., et al. (2014) Environmental Toxic. Pharm. 38(2): 438–443.
Raf-1 kinase inhibitor
Not a hazardous substance or mixture.
Safety Phrases:
S22 – Do not breathe dust.
S24/25 – Avoid contact with skin and eyes.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.