SR 3576__JNK3 kinase inhibitor Arg-Gly-Asp-Ser
Product Name
SR 3576
Description
JNK3 kinase inhibitor
Purity
>98% (HPLC)
CAS No.
1164153-22-3
Molecular Formula
C27H27N5O5
Molecular Weight
501.5
Storage Temperature
-20ºC
Shipping Temperature
Shipped Ambient
Product Type
Inhibitor
Solubility
Soluble to 100 mM in DMSO
Source
Synthetic
Appearance
Off White solid
InChI
InChI=1S/C27H27N5O5/c1-17-7-5-9-19(11-17)30-27(34)31-21-15-28-32(16-21)22-10-6-8-18(12-22)26(33)29-20-13-23(35-2)25(37-4)24(14-20)36-3/h5-16H,1-4H3,(H,29,33)(H2,30,31,34)
InChIKey
MTFAYLZZDJGFGV-UHFFFAOYSA-N
Safety Phrases
Classification:
Not a hazardous substance or mixture.
Safety Phrases:
S22 – Do not breathe dust.
S24/25 – Avoid contact with skin and eyes.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.
Cite This Product
SR 3576 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-513)
Alternative Names
SR3576, 3-(5-(3-m-Tolylureido)-1H-indazol-1-yl)-N-(3,4,5-trimethoxyphenyl)benzamide, 3-4-(3-Methylphenyl)aminocarbonylamino-1H-pyrazol-1-yl-N-(3,4,5-trimethoxyphenyl)-benzamide
Research Areas
Cancer, Apoptosis, Cancer Growth Inhibitors, Cell Signaling, Tyrosine Kinase Inhibitors
PubChem ID
70702008
Scientific Background
SR 3576 is a highly potent and selective JNK3 inhibitor. SR 3576 is a pyrazolourea compound and is cell-permeable.
References
1. Kamenecka T., et al. (2009) J. Biol. Chem. 284(19): 12853–12861.
JNK3 kinase inhibitor
Not a hazardous substance or mixture.
Safety Phrases:
S22 – Do not breathe dust.
S24/25 – Avoid contact with skin and eyes.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.