SRPIN340__SR kinase inhibitor Cinacalcet (hydrochloride)
Product Name
SRPIN340
Description
SR kinase inhibitor
Purity
>98%
CAS No.
218156-96-8
Molecular Formula
C18H18F3N3O
Molecular Weight
349.4
Storage Temperature
-20ºC
Shipping Temperature
Shipped Ambient
Product Type
Inhibitor
Solubility
Soluble to 100 mM in DMSO and to 50 mM in 1eq. HCl
Source
Synthetic
Appearance
Off-white solid
SMILES
C1CCN(CC1)C2=C(C=C(C=C2)C(F)(F)F)NC(=O)C3=CC=NC=C3
InChI
InChI=1S/C18H18F3N3O/c19-18(20,21)14-4-5-16(24-10-2-1-3-11-24)15(12-14)23-17(25)13-6-8-22-9-7-13/h4-9,12H,1-3,10-11H2,(H,23,25)
InChIKey
DWFGGOFPIISJIT-UHFFFAOYSA-N
Safety Phrases
Classification:
Not a hazardous substance or mixture.
Safety Phrases:
S22 – Do not breathe dust.
S24/25 – Avoid contact with skin and eyes.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.
Cite This Product
SRPIN340 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-514)
Alternative Names
N-2-(1-Piperidinyl)-5-(trifluoromethyl)phenyl-4-pyridinecarboxamide
Research Areas
Cancer, Apoptosis, Cancer Growth Inhibitors, Cell Signaling, Tyrosine Kinase Inhibitors
PubChem ID
2797577
Scientific Background
SRPIN340 is a selective inhibitor of serine–arginine protein kinases (SRPK). It has been shown to inhibit SRPK1, as well as, SRPK2, at higher concentrations. SRPIN340 is ATP-competitive.
References
1. Karakama Y., et al. (2010). Antimicrobial Agents Chemo. 54(8): 3179–3186.
SR kinase inhibitor
Not a hazardous substance or mixture.
Safety Phrases:
S22 – Do not breathe dust.
S24/25 – Avoid contact with skin and eyes.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.