Stattic__STAT3 inhibitor (3R,5S)-Tofacitinib
Product Name
Stattic
Description
STAT3 inhibitor
Purity
>98% (TLC); NMR (Conforms)
CAS No.
19983-44-9
Molecular Formula
C8H5NO4S
Molecular Weight
211.2
Storage Temperature
-20ºC
Shipping Temperature
Blue Ice or 4ºC
Product Type
Inhibitor
Solubility
May be dissolved in DMSO (10 mg/ml); or ethanol (1 mg/ml)
Source
Synthetic
Appearance
Light yellow powder
SMILES
C1=CC(=CC2=C1C=CS2(=O)=O)N+(=O)O-
InChI
InChI=1S/C8H5NO4S/c10-9(11)7-2-1-6-3-4-14(12,13)8(6)5-7/h1-5H
InChIKey
ZRRGOUHITGRLBA-UHFFFAOYSA-N
Safety Phrases
WHMIS Classification:
D2B – Toxic Material Causing Other Toxic Effects. Moderate skin irritant. Moderate respiratory irritant. Moderate eye irritant
GHS Classification:
Acute toxicity, Oral (Category 4)
Skin irritation (Category 2)
Eye irritation (Category 2A)
Specific target organ toxicity – single exposure (Category 3)
Signal word: Warning
Hazard statement(s):
H302 Harmful if swallowed.
H315 Causes skin irritation.
H319 Causes serious eye irritation.
H335 May cause respiratory irritation.
Precautionary statement(s):
P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray.
P264 Wash skin thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/ eye protection/ face protection.
P301 + P312 IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell.
P302 + P352 IF ON SKIN: Wash with plenty of soap and water.
P304 + P340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312 Call a POISON CENTER/doctor if you feel unwell.
P321 Specific treatment (see supplemental first aid instructions on this label).
P330 Rinse mouth.
P332 + P313 If skin irritation occurs: Get medical advice/ attention.
P337 + P313 If eye irritation persists: Get medical advice/ attention.
P362 Take off contaminated clothing and wash before reuse.
P403 + P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/ container to an approved waste disposal plant.
Cite This Product
Stattic (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-554)
Alternative Names
Stattic, 6-nitro-1-benzothiophene 1,1-dioxide, 6-Nitrobenzobthiophene 1,1-dioxide, Stat three inhibitory compound, STAT3 Inhibitor V, Stattic
Research Areas
Cancer, Alzheimer_s Disease, Cell Signaling, DNA Synthesis, DNA/RNA, Epigenetics and Nuclear Signalling, Neurodegeneration, Neuroscience, Stem Cells, Transcription, Transcription Factors
PubChem ID
2779853
STAT3 inhibitor
D2B – Toxic Material Causing Other Toxic Effects. Moderate skin irritant. Moderate respiratory irritant. Moderate eye irritant
GHS Classification:
Acute toxicity, Oral (Category 4)
Skin irritation (Category 2)
Eye irritation (Category 2A)
Specific target organ toxicity – single exposure (Category 3)
Signal word: Warning
Hazard statement(s):
H302 Harmful if swallowed.
H315 Causes skin irritation.
H319 Causes serious eye irritation.
H335 May cause respiratory irritation.
Precautionary statement(s):
P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray.
P264 Wash skin thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/ eye protection/ face protection.
P301 + P312 IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell.
P302 + P352 IF ON SKIN: Wash with plenty of soap and water.
P304 + P340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312 Call a POISON CENTER/doctor if you feel unwell.
P321 Specific treatment (see supplemental first aid instructions on this label).
P330 Rinse mouth.
P332 + P313 If skin irritation occurs: Get medical advice/ attention.
P337 + P313 If eye irritation persists: Get medical advice/ attention.
P362 Take off contaminated clothing and wash before reuse.
P403 + P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/ container to an approved waste disposal plant.