TCID__DUB inhibitor Tenofovir
Product Name
TCID
Description
DUB inhibitor
Purity
>97%
CAS No.
30675-13-9
Molecular Formula
C9H2Cl4O2
Molecular Weight
283.9
Storage Temperature
-20ºC
Shipping Temperature
Shipped Ambient
Product Type
Inhibitor
Solubility
Soluble in 25 mg/ml DMSO
Source
Synthetic
Appearance
White Solid
SMILES
C1C(=O)C2=C(C1=O)C(=C(C(=C2Cl)Cl)Cl)Cl
InChI
InChI=1S/C9H2Cl4O2/c10-6-4-2(14)1-3(15)5(4)7(11)9(13)8(6)12/h1H2
InChIKey
IDLAOWFFKWRNHB-UHFFFAOYSA-N
Safety Phrases
Classification: Caution – Substance not yet fully tested.
Safety Phrases:
S22 – Do not breathe dust
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection
S24/25- Avoid contact with skin and eyes
Precautionary Statements:
P260- Do not breathe dust/fume/gas/mist/vapours/spray.
P285- In case of inadequate ventilation wear respiratory protection.
P305+P351+P338- IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P310- Immediately call a POISON CENTER or doctor/physician.
P501- Dispose of contents/container in accordance with international regulations.
Hazard Statements:
H334- May cause allergy or asthma symptoms or breathing difficulties if inhaled
H373- May cause damage to organs through prolonged or repeated exposure
H318- Causes serious eye damage
H410- Very toxic to aquatic life with long lasting effects
H317- May cause an allergic skin reaction
Cite This Product
TCID (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-340)
Alternative Names
4,5,6,7-tetrachloro-1H-indene-1,3(2H)-dione
Research Areas
Cancer, Apoptosis
PubChem ID
2729042
Scientific Background
Inhibits ubiquitin C-terminal hydrolase L3 (UCH UCHL3). IC50=0.6 M, 125-fold selective over UCHL1, IC50=75 M. Cell permeable.
References
1. Love K.R., et al. (2007) Nat. Chem. Biol. 3: 697.
2. Mtango N.R. et al. (2012) J. Cell Physiol. 227: 2022.
DUB inhibitor
Safety Phrases:
S22 – Do not breathe dust
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection
S24/25- Avoid contact with skin and eyes
Precautionary Statements:
P260- Do not breathe dust/fume/gas/mist/vapours/spray.
P285- In case of inadequate ventilation wear respiratory protection.
P305+P351+P338- IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P310- Immediately call a POISON CENTER or doctor/physician.
P501- Dispose of contents/container in accordance with international regulations.
Hazard Statements:
H334- May cause allergy or asthma symptoms or breathing difficulties if inhaled
H373- May cause damage to organs through prolonged or repeated exposure
H318- Causes serious eye damage
H410- Very toxic to aquatic life with long lasting effects
H317- May cause an allergic skin reaction
2. Mtango N.R. et al. (2012) J. Cell Physiol. 227: 2022.