TPCK__Serine protease inhibitor Entecavir (monohydrate)
Product Name
TPCK
Description
Serine protease inhibitor
Purity
>98%
CAS No.
402-71-1
Molecular Formula
C17H18CI3O3S
Molecular Weight
351.85
Storage Temperature
-20ºC
Shipping Temperature
Shipped Ambient
Product Type
Inhibitor
Solubility
Soluble in DMSO (>10 mg/ml) and in 10 mM in methanol and ethanol (50 mg/ml)
Source
Synthetic
Appearance
White Solid
SMILES
ClCC(=O)C(NS(=O)(=O)c1ccc(cc1)C)Cc2ccccc2
InChI
InChI=1S/C17H18ClNO3S/c1-13-7-9-15(10-8-13)23(21,22)19-16(17(20)12-18)11-14-5-3-2-4-6-14/h2-10,16,19H,11-12H2,1H3/t16-/m0/s1
InChIKey
MQUQNUAYKLCRME-INIZCTEOSA-N
Safety Phrases
Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin.
Safety Phrases:
S22 – Do not breathe dust
S24/25 – Avoid contact with skin and eyes
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection
Risk Phrases: 37/38-41
Hazard Phrases:
H315-H318-H335
Precautionary Phrases:
P261-P280-P305 + P351 + P338
Cite This Product
TPCK (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-207)
Alternative Names
N-(4-Chloro-3-oxo-1-phenyl-2-butanyl)-4-methylbenzenesulfonamide
Research Areas
Cancer, Apoptosis
PubChem ID
9824
Scientific Background
Tosyl phenylalanyl chloromethyl ketone is a protease inhibitor. It also inhibits some cysteine proteases (1).
References
1. Farrelll S.O., Campbell M.K. (2006) Biochemistry. Australia: Thomson Brooks/Cole. P.160.
Serine protease inhibitor
Safety Phrases:
S22 – Do not breathe dust
S24/25 – Avoid contact with skin and eyes
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection
Risk Phrases: 37/38-41
Hazard Phrases:
H315-H318-H335
Precautionary Phrases:
P261-P280-P305 + P351 + P338