Valinomycin__Apoptosis Inducer VcMMAE
Product Name
Valinomycin
Description
Apoptosis Inducer
Purity
>98%
CAS No.
2001-95-8
Molecular Formula
C54H90N6O18
Molecular Weight
1111.32
Storage Temperature
-20ºC
Shipping Temperature
Shipped Ambient
Product Type
Inducer
Solubility
Soluble to 25 mM in DMSO
and 25 mM in ethanol.
Source
Synthetic
Appearance
White Solid
SMILES
Cemail protected1C(=O)Nemail protected(C(=O)OC@@H(C(=O)NC@@H(C(=O)Oemail protected(C(=O)Nemail protected(C(=O)OC@@H(C(=O)NC@@H(C(=O)Oemail protected(C(=O)Nemail protected(C(=O)OC@@H(C(=O)NC@@H(C(=O)O1)C(C)C)C(C)C)C(C)C)C)C(C)C)C(C)C)C(C)C)C)C(C)C)
InChI
InChI=1S/C54H90N6O18/c1-22(2)34-49(67)73-31(19)43(61)55-38(26(9)10)53(71)77-41(29(15)16)47(65)59-36(24(5)6)51(69)75-33(21)45(
InChIKey
FCFNRCROJUBPLU-UYBNATROSA-N
Safety Phrases
Classification: Very Toxic. May be fatal if inhaled, swallowed or absorbed through skin.
Safety Phrases:
S22 – Do not breathe dust
S24/25 – Avoid contact with skin and eyes
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection
S45 – In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible)
Risk Phrases:
R23/24/25 – Toxic by inhalation, in contact with skin and if swallowed
R68 – Possible risk of irreversible effects
Hazard Phrases:
H300-H310
Precautionary Phrases:
P264-P280-P302 + P350-P310
Cite This Product
Valinomycin (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-230)
Alternative Names
(3R,6R,9S,12S,15R,18R,21S,24S,27R,30R,33S,36S)-3,6,9,15,18,21,27,30,33-Nonaisopropyl-12,24,36-trimethyl-1,7,13,19,25,31-hexaoxa-4,10,16,22,28,34-hexaazacyclohexatriacontane-2,5,8,11,14,17,20,23,26,29, 32,35-dodecone
Research Areas
Cancer, Apoptosis
PubChem ID
5649
Scientific Background
Valinomycin is a dodecadepsipeptide, and a member of a group of natural neutral ionophores. It is highly selective for potassium ions within the cell membrane (1). It functions as a potassium-specific transporter and facilitates the movement of potassium ions through lipid membranes down an electrochemical potential gradient (2).
References
1. Lars R., Jenkins A.T.A. (2007) Bioelectrochem. 70(2): 387-393.
2. Cammann K. (1985) Top Curr Chem. 128: 219-258.
Apoptosis Inducer
and 25 mM in ethanol.
Safety Phrases:
S22 – Do not breathe dust
S24/25 – Avoid contact with skin and eyes
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection
S45 – In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible)
Risk Phrases:
R23/24/25 – Toxic by inhalation, in contact with skin and if swallowed
R68 – Possible risk of irreversible effects
Hazard Phrases:
H300-H310
Precautionary Phrases:
P264-P280-P302 + P350-P310
2. Cammann K. (1985) Top Curr Chem. 128: 219-258.