Vandetanib__VEGFRK inhibitor IPI551
Product Name
Vandetanib
Description
VEGFRK inhibitor
Purity
>98% (HPLC)
CAS No.
443913-73-3
Molecular Formula
C22H24BrFN4O2
Molecular Weight
475.4
Storage Temperature
-20ºC
Shipping Temperature
Shipped Ambient
Product Type
Inhibitor
Solubility
Soluble in DMSO (30 mg/ml) or EtOH (10 mg/ml)
Source
Synthetic
Appearance
Yellow solid
SMILES
C1=C3C(=CC(=C1OC)OCC2CCN(CC2)C)N=CN=C3NC4=CC=C(Br)C=C4F
InChI
InChI=1S/C22H24BrFN4O2/c1-28-7-5-14(6-8-28)12-30-21-11-19-16(10-20(21)29-2)22(26-13-25-19)27-18-4-3-15(23)9-17(18)24/h3-4,9-11,13-14H,5-8,12H2,1-2H3,(H,25,26,27)
InChIKey
UHTHHESEBZOYNR-UHFFFAOYSA-N
Safety Phrases
Classification:
Not a hazardous substance or mixture.
Safety Phrases:
S22 – Do not breathe dust.
S24/25 – Avoid contact with skin and eyes.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.
Cite This Product
Vandetanib (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-483)
Alternative Names
N-(4-bromo-2-fluorophenyl)-6-methoxy-7-(1-methylpiperidin-4-yl)methoxyquinazolin-4-amine
Research Areas
Cancer, Apoptosis, Cancer Growth Inhibitors, Cardiovascular System, Cell Signaling, Growth Factor Receptor Inhibitors
PubChem ID
3081361
Scientific Background
Vandetanib is a specific inhibitor of Flk-1 and Flt-4.
References
1. Bruns C.J., et al. (2000) Clin. Cancer. Res: J. Am. Assoc. Cancer Res. 6(5): 1936–1948.
VEGFRK inhibitor
Not a hazardous substance or mixture.
Safety Phrases:
S22 – Do not breathe dust.
S24/25 – Avoid contact with skin and eyes.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.