Z-Asp-CH2-DCB

Z-Asp-CH2-DCB__Caspase inhibitor RN488

Product Name Z-Asp-CH2-DCB
Description

Caspase inhibitor

Purity >99%
CAS No. 153088-73-4
Molecular Formula C20H17Cl2NO7
Molecular Weight 454.3
Storage Temperature -20ºC
Shipping Temperature Shipped Ambient
Product Type Inhibitor
Solubility Soluble in methanol (50 mg/ml) or DMSO
Source Synthetic
Appearance White to off-white Solid
SMILES C1=CC=C(C=C1)COC(=O)NC@@H(CC(=O)O)C(=O)COC(=O)C2=C(C=CC=C2Cl)Cl
InChI InChI=1S/C20H17Cl2NO7/c21-13-7-4-8-14(22)18(13)19(27)29-11-16(24)15(9-17(25)26)23-20(28)30-10-12-5-2-1-3-6-12/h1-8,15H,9-11H2,(H,23,28)(H,25,26)/t15-/m0/s1
InChIKey FKJMFCOMZYPWCO-HNNXBMFYSA-N
Safety Phrases Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin.
Safety Phrases:
S22 – Do not breathe dust
S24/25 – Avoid contact with skin and eyes
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection
Cite This Product Z-Asp-CH2-DCB (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-206)
Alternative Names (3S)-3-{(Benzyloxy)carbonylamino}-5-(2,6-dichlorobenzoyl)oxy-4-oxopentanoic acid
Research Areas Cancer, Apoptosis
PubChem ID 9911778
Scientific Background Irreversible, cell permeable broad-spectrum caspase inhibitor. Inhibits hypoxia-induced apoptosis in neuroblastoma cells.