(R, S)-Niguldipine HCl__Ca2+ channel blocker AP20187
Product Name
(R, S)-Niguldipine HCl
Description
Ca2+ channel blocker
Purity
>98%
CAS No.
119934-51-9
Molecular Formula
C36H39N3O6•HCl
Molecular Weight
646.18
Storage Temperature
-20ºC
Shipping Temperature
Shipped Ambient
Product Type
Inhibitor
Solubility
Soluble to 10 mM in water
Source
Synthetic
Appearance
Yellow solid
Safety Phrases
Classification: Caution: Substance not yet fully tested.
Safety Phrases:
S22 – Do not breathe dust
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection
S24/25- Avoid contact with shin and eyes
Cite This Product
(R, S)-Niguldipine HCl (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-319)
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/19110085
Alternative Names
(R,S)-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid, 3-(4,4-diphenyl-1-piperidinyl)propyl methyl ester hydrochloride
Research Areas
Calcium Channels, Ion Channels, Neuroscience, Voltage-Gated Calcium Channels
Scientific Background
Niguldipine is a calcium channel blocker and an a1-adrenergic receptor antagonist.
References
1. Boer R., Grassegger A., Schudt C., Glossman H. (1999) Eur J Pharmacol. 172(2): 131-145.
2. Robinson J.P., Kendall D.A. (1990) Br J Pharmacol. 100(1): 3-4.
Ca2+ channel blocker
Safety Phrases:
S22 – Do not breathe dust
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection
S24/25- Avoid contact with shin and eyes
2. Robinson J.P., Kendall D.A. (1990) Br J Pharmacol. 100(1): 3-4.