Learning, a hippocampus-dependent type of memory, which is identified to become particularly vulnerable beneath various pathological conditions. Systemic LPS injection inhibits hippocampal long-term potentiation (LTP) (Vereker et al. 2000) and selectively impairs hippocampus-dependent spatial navigation in the Morris water maze and contextual fear conditioning, whereas cortex-independent auditory-cue fear conditioning remains unaffected (Rachal Pugh et al. …
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