Xpand upon earlier perform and reveal a direct capacity of GnRH signalling to downregulate melatonin receptor expression in aT3-1 gonadotroph cells. In spite of this effect and also the elevated Mt1 previously observed in hypogonadal mice, blockade of GnRH signalling in adult animals didn’t increase pituitary Mt1 mRNA. Together these Epigenetics findings suggest that GnRH …
Continue reading “Xpand upon earlier operate and reveal a direct capacity of GnRH”