The portrayal of palliative sedation in Tibbetts’ CMAJ article misleads readers by conflating it with euthanasia and suggesting it is routinely used to hasten death. This mischaracterization not only distorts…
Intellectual disability (ID), formerly known as mental retardation, is characterized by significant limitations in intellectual functioning and adaptive behavior, manifesting before age 18. It affects approximately 2–3% of the population…
Mitochondria play a central role in cellular metabolism and are vital to numerous biological processes. Among their key functions is the maintenance of mitochondrial membrane potential (MMP), which serves as…
In recent years, the neurotoxic potential of inhalational anesthetics has drawn significant attention, particularly in vulnerable populations such as elderly patients and those with pre-existing neurodegenerative conditions. Among these agents,…
A 69-year-old cachectic man presented to the accident and emergency department with tachycardia, hypotension, and a 7-day history of persistent vomiting and constipation. Notably, he reported no significant abdominal pain.…
Plasmodium vivax remains the predominant malaria parasite in China, particularly in regions like Yunnan Province, which experiences both vivax and falciparum malaria transmission. As part of national efforts to eliminate…
The accumulation of amyloid-β (Aβ) in the brain is a hallmark of Alzheimer’s disease, yet its distribution across brain regions is not uniform. Understanding why certain areas are more vulnerable…
Erlotinib, a tyrosine kinase inhibitor, is clinically approved for treating advanced non-small cell lung cancer (NSCLC). While it extends survival, its efficacy remains limited due to intrinsic or acquired resistance…
RNA molecules play essential roles in numerous biological processes, with their functions often dependent on specific three-dimensional conformations. The secondary structure of RNA—formed by base pairing within a single strand…
**Background** Attention deficit hyperactivity disorder (ADHD) is a complex neurodevelopmental disorder characterized by persistent patterns of inattention, hyperactivity, and impulsivity. These symptoms are closely linked to dysregulation of key neurotransmitters…