Pective analysis of patients with diagnosis of gallbladder cancer among ,inside a referral tertiary center. Results: We integrated sufferers ( ladies),having a median age of years. The median time of followup was months,with a mortality rate of (n. The majority of individuals PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/21046372 ( had history of cholelithiasis and have been diagnosed after cholecystectomy ( of those inside the context of acute cholecystitis). Essentially the most common symptoms reported at admission had been abdominal discomfort (jaundice (and nauseavomiting The majority in the patients had slight cholestasis in laboratorial analysis. The neoplasms involved the gallbladder physique or had been panvesicular in of situations. A nonspecific adenocarcinoma was one of the most prevalent diagnosis (using a median size of mm. At diagnosis, have been in an advanced stage (IIIIV). A surgery of curative intent was performed in of individuals. The palliative approaches a lot more regularly made use of were percutaneous drainage ( and chemorradiotherapy An endoscopic drainage was performed only in individuals The mortality rate at ,,and JI-101 chemical information months was ,, and ,respectively. The presence of cholestasis (p.) and renal dysfunction (p.) at diagnosis correlated independently with early mortality. Conclusion: The gallbladder carcinoma was additional prevalent in women with sophisticated age,in quite a few cases with prior cholelithiasis and in an advanced stage at diagnosis. Adenocarcinoma was the most prevalent histological sort. Regardless of the higher price of surgical approaches for curative intent, did not survive beyond years following the diagnosis. Disclosure of Interest: None declaredUnited European Gastroenterology Journal (S) Abstract number P Table . Hepatogastrostomy jejunostomy[HG(J)S] Variety of the pts (AB) MaleFemale Mean age (range) years Malignities Benign pathologies Indications (AB) Technical good results price AB (Quantity of the individuals)# Really serious Complications:AB [ . ] (Bleeding in two casesone died,a single surgery; cholangitis and sepsis in one case; perforation in two situations (surgery necessary) Choledocho or cystoduodenostomy [CD(Cy)S] [ ] (Bile leak and biloma formation ( cm) requiring surgery in onecardiopulmonary arrest and death in 1) CholecystoCholedochalRendezvous gastrostomy(CRV) jejunostomy[CG(J)S] Total [ ] (Surgery as a consequence of guidewire knotting in duodenum) [ A[ . ]] ( death,surgery,extended intensive care keep)P DIRECT RETROGRADE CHOLANGIOSCOPYDIRECTED BIOPSY IS SUPERIOR TO FLUOROSCOPYGUIDED BIOPSY TO DIFFERENTIATE INDETERMINATE BILIARY STRICTURE Within the DISTAL Prevalent BILE DUCT,BUT NOT Inside the PORTA HEPATIS D. Walter,M. FriedrichRust,S. Zeuzem,J. Albert Healthcare Division ,University hospital Frankfurt,Frankfurt,Germany Get in touch with Email Address: dirk.walterkgu.de Introduction: Differentiation of indeterminate biliary stricture (IBS) by imaging modalities is restricted. Definite diagnosis is based on histopathology,but high prices of false unfavorable biopsies constrain the clinical management. Aims Approaches Aims: To investigate purpose of high false adverse final results of intraductal biopsies obtained below fluoroscopic guidance in comparison to direct retrograde cholangioscopy (DRC). Approaches: All sufferers have been retrospectively included who presented for diagnostic workup of IBS at our University hospital and who underwent an intraductal biopsy amongst and . Histopathological results of fluoroscopic vs DRCdirected intraductal biopsies were compared with the golden regular of either postoperative histology or followup of at the very least a single year and underlying disease of false negative biopsies.