41 (one hundred ) 156 (64.70 ) 44 (18.30 ) 39 (16.20 ) 27 (11.20 ) 25 (ten.40 )TABLE 4: VRE sensitivitiesVRE, vancomycin-resistant EnterococcusOver a period of seven years, the total quantity of individuals diagnosed with VRE infection decreased from 50 cases in 2015 to 26 instances in 2021. Frequency of E. species infection decreased from 66 to 62 , but the frequency of E. faecium infections elevated from 34 to 38 . Frequency of bacteremia decreased from 54 to 31 , and that of intra-abdominal infections decreased from four to two . Frequency of urinary tract infections improved from 32 to 35 . Frequency of ICU admission enhanced from 26 to 35 , and that of mortality enhanced from 24 to 35 . Results are summarized in Table five.2015 N=50 N ( ) Infection traits E. species E. faecium Bacteremia UTI IAI Pneumonia SSRI Bone and joint infection ICU admission 30-day mortality 33 (66 ) 17 (34 ) 27 (54 ) 16 (32 ) four (eight ) 2 (four ) four (8 ) 13 (26 ) 12 (24 )2016 N=31 N ( )2017 N=51 N ( )2018 N=36 N ( )2019 N=29 N ( )2020 N=18 N ( )2021 N=26 N ( )29 (93.5 ) 2 (six.five ) 16 (52 ) 12 (39 ) two (6.five ) four (13 ) 1 (three.two ) 18 (58 ) 18 (58 )31 (61 ) 20 (39 ) 14 (27 ) 22 (43 ) three (6 ) 1 (2 ) five (ten ) 25 (49 ) 25 (49 )14 (39 ) 22 (61 ) 19 (52 ) five (14 ) six (17 ) 3 (8.three ) 2 (five.six ) 1 (two.7 ) 23 (64 ) 23 (64 )17 (58.six ) 12 (41.4 ) 15 (52 ) six (21 ) 1 (three.four ) three (ten ) 14 (48 ) 13( 45 )7 (39 ) 11 (61 ) ten (56 ) eight (44 ) eight (44 ) eight (44 )16 (62 ) ten (38 ) eight (31 ) 9 (35 ) two (7.Cariporide manufacturer 7 ) three (11.MSAB Purity & Documentation 5 ) 3 (11.five ) 9 (35 ) 9 (35 )Comorbidities AKI DM AKI+IHD Clostridium difficile IHD Prior admission Recurrence 7 (14 ) 7 (14 ) four (8 ) 1 (two ) 41 (82 ) 8 (16 ) 11 (35 ) 10 (32 ) 24 (77 ) 3 (9.7 ) 14 (27 ) 14 (27 ) 1 (two ) 40 (78 ) eight (16 ) 16 (44 ) 15 (42 ) 1 (2.7 ) 32 (89 ) two (five.six ) 9 (31 ) 9 (31 ) 1 (3.4 ) 2 (7 ) 27 (93 ) 1 (three.four ) five (28 ) 5 (28 ) 1 (5.6 ) 13 (72 ) 1 (five.six ) 10 (38 ) ten (38 ) 21 (81 ) 3 (11.five )2022 Rafey et al. Cureus 14(11): e31335. DOI 10.7759/cureus.six ofMalignancy Pre-B ALL Burkitt’s lymphoma DLBCL Hodgkin lymphoma AML CLL A number of myeloma CA breast CA urinary bladder Osteosarcoma CA colon Renal cell CA CA ovary CA esophagus CA pancreas CA lung CA prostate CA stomach CA gallbladder 13 (26 ) 10 (20 ) 7 (14 ) 3 (six ) 1 (two ) two (four ) 1 (two ) 2 (four ) 2 (four ) two (4 ) two (four ) three (six ) 1 (2 ) 2 (4 ) 6 (19 ) four (13 ) 8 (26 ) five (16 ) 1 (3.PMID:23399686 2 ) three (9.7 ) 1 (three.two ) three (9.7 ) 2 (six.5 ) 2 (six.five ) 1 (three.2 ) 14 (27 ) 5 (ten ) 2 (4 ) 2 (4 ) two (4 ) four (8 ) 1 (2 ) 4 (eight ) 2 (4 ) 1 (two ) 2 (4 ) 3 (6 ) 2 (four ) 11 (30.1 ) five (13.9 ) three (8.three ) 3 (8.3 ) two (5.six ) two (5.6 ) 1 (two.7 ) 2 (5.6 ) 1 (two.7 ) four (11 ) 1 (two.7 ) two (five.six ) two (5.6 ) 1 (2.7 ) 1 (3.four ) 4 (14 ) four (14 ) 2 (7 ) 1 (three.4 ) 1 (3.four ) 2 (7 ) four (14 ) 1 (3.4 ) 1 (three.4 ) 1 (3.four ) 1 (three.four ) 1 (three.four ) 3 (16.7 ) six (33.3 ) 1 (five.6 ) 2 (11 ) two (11 ) two (11 ) two (11 ) 1 (five.six ) two (11 ) 1 (five.6 ) 1 (5.6 ) 1 (5.six ) 1 (3.8 ) six (23 ) 1 (three.8 ) 2 (7.7 ) five (19 ) 2 (7.7 ) 1 (three.8 ) 1 (3.eight ) 2 (7.7 ) 1 (three.8 )TABLE 5: Trends of VRE infectionUTI, urinary tract infection; IAI, intra-abdominal infection; SSRI, skin and skin-related infection; AKI, acute kidney injury; DM, diabetes mellitus; IHD, ischemic heart illness; pre-B ALL, precursor B cell acute lymphoblastic leukemia; DLBCL, diffuse massive B cell lymphoma; AML, acute myeloid leukemia; CLL, chronic lymphocytic leukemia; CA, cancer; VRE, vancomycin-resistant EnterococcusFrequency of fosfomycin and chloramphenicol sensitivity decreased from 20 to 15 and 62 to 54 , respectively, whereas sensitivity of tetracycline and nitrofurantoin improved from 8 to 31 and.